邵太丽
时间:2023-10-17 来源:药学院 阅读次数:邵太丽,汉,博士研究生,教授。荣获安徽省教学成果二等奖(2019jxcgj291),校级教学成果二等奖(2017jxcgj04-8)。参编教材情况:共同副主编全国高职高专“十三五”规划教材《药物化学》。近期教研成果:参与教研项目安徽省精品课程(2013gxk061),支持校级教研项目(2020kcbz04)。指导国家级大学生创新创业训练计划项目(201510368012)。
【主要研究方向】从事多糖分离、纯化、修饰及结构解析方面的基础研究。
【联系方式】0553-3932026;shaotaili@wnmc.edu.cn
【教育学习经历】
2011年09月——2015年06月 安徽师范大学有机化学专业 博士
2003年09月——2007年06月 沈阳药科大学药物化学专业 硕士
1999年09月——2003年06月 沈阳药科大学制药工程专业 学士
【主要科研项目】
1、安徽高校自然科学研究重大项目, 基于SIRT1/LKB1/AMPK通路探讨甜叶菊根多糖改善非酒精性脂肪肝病的机制研究, 项目编号:KJ2021ZD0101(参与,在研)
2、菊糖硒纳米颗粒的制备及活性研究. 2022年安徽省多糖药物工程技术研究中心(皖南医学院)校级课题, 项目编号:WKGC202001(主持,已结题)
3、皖南医学院博士科研启动基金项目,项目编号:WYRCQD201711(主持,已结题)
【近五年代表性论文】
1、Zhiyan Tang1, Taili Shao1, Lan Gao, Pingchuan Yuan, Zhengrui Ren, Lei Tian, Wei Liu, Chunyan Liu, Xiuxian Xu, Xuan Zhou, Jun Han, Guodong Wang. Structural elucidation and hypoglycemic effect of an inulin-type fructan extracted from Stevia rebaudiana roots, Food & Function, 2023, 14: 2518-2529.
2、Chunyan Liu, Pingchuan Yuan, Ying Wang, Xuelian Yang, Yudie Xu, Wenzhi Zhang, Xue Han, Kaoshan Chen, Guodong Wang, Taili Shao*. Effects of burdock inulin-type fructans exposure on the physiological function of healthy mice and their filial generation, J. Vet. Med. Sci. 85(4): 425–433, 2023
3、Wei Liu1, Taili Shao1, Lei Tian, Zhengrui Ren, Lan Gao, Zhiyan Tang, Zheng Fang, Pingchuan Yuan, Chunyan Liu, Jikun Li, Guodong Wang, Jun Han. Structural elucidation and anti-nonalcoholic fatty liver disease activity of Polygonatum cyrtonema Hua polysaccharide, Food & Function, 2022, 13(24): 12883-12895.
4、Jiaojiao Wang, Pingchuan Yuan, Wenzhi Zhang, Chunyan Liu, Kaoshan Chen, Guodong Wang and Taili Shao*. Separation, Purification, Structural Characterization, and Anticancer Activity of a Novel Exopolysaccharide from Mucor sp., Molecules, 2022, 27, 2071.
5、Taili Shao, Pingchuan Yuan, Wenzhi Zhang, Deyu Dou, Fengge Wang, Chengyi Hao, Chunyan Liu, Jun Han, Kaoshan Chen, Guodong Wang. Preparation and characterization of sulfated inulin-type fructans from Jerusalem artichoke tubers and their antitumor activity, Carbohydrate Research, 2021, 509: 108422.
6、Taili Shao, Wei Liu, Pingchuan Yuan, Xichen Li, Honggang Xu, Chunyan Liu, Kaoshan Chen, Lihua Li, Jun Han, Guodong Wang. Enhanced antitumor activity of inulin-capped Se nanoparticles synthesized using Jerusalem artichoke tubers, Glycoconjugate Journal, 2021, 38(5): 599-607.
7、Taili Shao, Pingchuan Yuan, Lei Zhu, Honggang Xu, Xichen Li, Shuguang He, Ping Li, Guodong Wang, and Kaoshan Chen. Carbon Nanoparticles Inhibit α-Glucosidase Activity and Induce a Hypoglycemic Effect in Diabetic Mice. Molecules, 2019, 24, 3257-3266.
8、Pingchuan Yuan1, Taili Shao1, Jun Han, Chun-yan Liu, Guodong Wang, Shuguang He, Shixia Xu, Sihui Nian, Kao-shan Chen. Burdock fructooligosaccharide as an α-glucosidase inhibitor and its antidiabetic effect on high-fat diet and streptozotocin-induced diabetic mice, Journal of Functional Foods, 2021, 86, 104703.